KU Leuven

PhD position on DNA-based artificial transmembrane nanomotors

2024-07-15 (Europe/Brussels)
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KU Leuven is an autonomous university. It was founded in 1425. It was born of and has grown within the Catholic tradition.

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We are a newly established research group at KU Leuven, founded in October 2023. Our team is part of the Biochemistry, Molecular, and Structural Biology division within the Department of Chemistry.
To learn more about our research, visit: Xinshilab.com
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Our society relies on machines and engines, and so does life. Molecular motors are widely found in different biosystems, e.g. the famous FoF1 ATP synthase motor that produces the fuel for our cells. Their sophisticated structures and functions established the foundations of the dynamics in the cellular world. The questions ahead for us are: what can we learn from them? Can we build such motors at the nanoscale? The fascinating world of biology has given us positive answers to these questions: we should be able to. With the support of the KU Leuven Special Research Fund (BOF), we are looking for outstanding experimentalists who are interested in and eager to participate in our research to redesign and create these marvellous machines at nanoscales. 

For this PhD project, the candidate will take the lead on designing and building the next generation of DNA-based nanoscale motors in lipid bilayers. The candidate will use DNA technology to construct the shapes of the DNA motor, use single-channel electrophysiology tools to control and manipulate these nanoscale artificial motors, and observe their motion and evaluate their performance using single-molecule localisation fluorescence microscopy. Experience in any of the above-mentioned techniques is welcomed, but not required. 
Check out our lab on xinshilab.com, and please contact Prof. Xin Shi (xin.shi@kuleuven.be) for more information.


  • Candidates must hold a Master’s degree in chemistry, biochemistry, biophysics (or equivalent), 
  • Enthusiasm for research in a collaborative environment, 
  • Excellent oral and written communication skills in English are required, 
  • Experience in (biological or solid-state) nanopores, DNA technology, single-molecule microscopy, and data analysis and programing is welcomed but not required.


FLOF funding is available for the entirety of the PhD. Initially, a 1-year contract will be provided, which will be extended in case of a positive evaluation in the first year.


For more information, please contact Prof. Xin Shi, xin.shi@kuleuven.be 

Please include a motivation letter and a CV with at least three references. Your cover letter and CV may be internally shared with the group and external committee members for review. 
KU Leuven seeks to foster an environment where all talents can flourish, regardless of gender, age, cultural background, nationality, or impairments. If you have any questions relating to accessibility or support, please contact us at diversiteit.HR@kuleuven.be.

KU Leuven strives for an inclusive, respectful and socially safe environment. We embrace diversity among individuals and groups as an asset. Open dialogue and differences in perspective are essential for an ambitious research and educational environment. In our commitment to equal opportunity, we recognize the consequences of historical inequalities. We do not accept any form of discrimination based on, but not limited to, gender identity and expression, sexual orientation, age, ethnic or national background, skin colour, religious and philosophical diversity, neurodivergence, employment disability, health, or socioeconomic status. For questions about accessibility or support offered, we are happy to assist you at this email address.

Dettagli del lavoro

PhD position on DNA-based artificial transmembrane nanomotors
Datore di lavoro
Oude Markt 13 Lovanio, Belgio
Scadenza candidatura
2024-07-15 23:59 (Europe/Brussels)
2024-07-15 23:59 (CET)
Tipo di lavoro
Salva lavoro

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Informazioni sul datore di lavoro

KU Leuven is an autonomous university. It was founded in 1425. It was born of and has grown within the Catholic tradition.

Visita la pagina del datore di lavoro