The Marie Skłodowska-Curie Actions Innovative Training Network "SINERGIA" looks for 15 motivated early-stage researcher (ESR)
All positions give the opportunity of the enrolment in a PhD program. The contracts will be for 36 months with a competitive salary (the precise amount depends on the Country and family status).
The SINERGIA Network is devoted to the development of novel in vitro preclinical models, based on 4 cutting-edge technologies: bioprintin, organs-on-chip, 3D cell culture and induced pluripotent stem cells. SINERGIA is funded under Marie Sklodowska-Curie actions (H2020-MSCA-ITN-2019, grant agreement number: 860715).
The Network comprises 10 beneficiaries and 4 partner organisations from both the academic and industrial sectors from 6 countries (Italy, Switzerland, The Netherlands, Czech Republic, Germany and United Kingdom).
The SINERGIA project provides research and training opportunities for early-stage researchers in the field the emerging technologies in drug development and precision medicine. Specifically, SINERGIA aims at improving the dialogue among the main stakeholders in the drug discovery field, and at developing advanced models of human physiology and diseases, to be ultimately introduced in the preclinical stages of the drug discovery pipeline.
SINERGIA’s research programme addresses three investigational areas of the drug development process – namely drug benefit, drug safety and precision medicine – with the aim of bringing advanced models built on innovative Technologies from bench to the pharmaceutical market. SINERGIA research objectives are: i) drug benefit, ii) drug safety, and iii) precision medicine.
Training will be achieved through research and by education. Research training includes Secondments at partner premises, Training by education includes transferable skills training and comprises attendance to both local training activities and network-wide training activities. In addition, ESRs will attend 3 SINERGIA Summer Schools. The ESRs will also have the opportunity to enroll for a PhD.
We are looking for highly motivated researchers with an excellent academic background in Bioengineering, Chemistry, Material Science, Biology and Physics.
Developing a miniaturized ex vivo culture system for drug testing on patient-specific tumour specimens.
Generation of a 3D in vitro model to study cardiac fibroblast contribution to myocardial fibrosis.
Kidney fibrosis in vitro model.
An in vitro model of skeletal muscle tissue to test anti-fibrotic therapies.
Multi-compartment microfluidic model to improve gut microbiome-mediated immunotherapy efficiency.
Bioprinting of kidney rudiment for drug safety screening.
uHeart: an in vitro human miniaturized model for the detection of drug-induced functional cardiotoxicity.
Set-up and preliminary validation of a modular high-throughput microfluidic system for assessing drug toxicity and metabolism in the hepatobiliary environment.
Validation of in vitro 3D liver model for efficacy and/or toxicology studies.
Development of an ex-vivo liver model to study drug treatment.
Engineering a perfusion-based bioreactor system to study metastatic breast cancer interactions with bone microenvironments.
Microfluidic bone chip to personalize the therapeutic regimen of bone metastatic tumours.
Validation of in vitro approaches for precision based medicine.
Development of a patient-specific a lab-on-chip cardiac microtissue model of dystrophin deficient cardiomyopathy.
All applicants must be Early-Stage Researchers (ESRs) who are in the first four years (full-time equivalent research experience) of their research careers, starting from the date when the M.Sc. degree (or similar) was awarded. They must not hold a doctoral degree.
Persons from any nationality may apply, but transnational mobility is indispensable: You may only apply for a position in a particular project if you did not reside or carry out your main activity (such as work or study) in this country for more than 12 months within the last 3 years. This excludes short stays such as holidays or compulsory national service.
The selected candidates will receive a 36-month, full-time employment contract as per Marie Sklodowska-Curie Actions (MSCA) regulations for early stage researchers. Marie Curie ITNs provide a highly competitive salary to the ESR, including a generous monthly living and mobility allowance and (if eligible) a monthly family allowance. The exact salary will be confirmed upon appointment. In particular, it consists of:
It must be noted that the living allowance is a gross EU contribution to the salary costs of the researcher. Consequently, the net salary results from deducting all compulsory social security contributions (employer and employee) as well as direct taxes (e.g. income tax) from the gross amounts. The rate indicated here is for researchers devoting themselves to their project on a full-time basis.
The mobility and family allowance is a fixed amount, regardless of the country of recruitment, and may be taxable depending on the country in which the researcher is recruited.
HOW TO APPLY
We are looking forward to hearing from you! Please download the application form via this link.
In order for your application to be considered please send the filled application form together with the following documents in English:
All the documents (including the application form!) must be submitted to email@example.com.
Detailed information to all ESR projects within the network can be found on our website www.sinergia2020.polimi.it. For further information and inquires please contact Prof. Marco Rasponi (marco.rasponi AT polimi.it)
Diversity is a core value of SINERGIA. We are an inclusive community, and we believe that diversity and international activities enhance the quality of research and training. We are looking for people who can enhance diversity in our team thanks to their background and experience.
Special attention will be paid to gender-equality. Female researchers are strongly encouraged to apply; in case of equal qualification in the recruitment procedure, the enrolment of female candidates will be prioritized.Continue reading
|Title||15 PhD/Early Stage Researcher (ESR) positions available as part of the MSCA European Training Network SINERGIA|
|Employer||Politecnico di Milano|
|Job location||Piazza Leonardo da Vinci, 32 20133 Milano|
|Published||November 26, 2019|
|Application deadline||January 1, 2020|
|Job types||PhD  |
|Fields||Biomedical Engineering,   Physiology,   Biomedicine,   Clinical Sciences,   Microbiology,   Cardiology,   Immunology,   Human Biology,   Immunochemistry,    and 2 more. Bioengineering,   Pharmacy & Pharmacology  |