→ Apply before 13/07/2024 (DD/MM/YYYY) 23:59 (Brussels Time)
→ Faculty of Bioscience Engineering
→ Department: BW25 - Biotechnologie
→ Occupancy rate: 100%
→ Number of positions: 1
→ Type of employment: Contract of unlimited duration with clause
→ Term of assignment: Initial contract of one year, extended upon positive evaluation
→ Wage scale: PD1 to PD4 (doctoral degree)
→ Required diploma: PhD
ABOUT GHENT UNIVERSITY
Ghent University is a world of its own. Employing more than 15,000 people, it is actively involved in education and research, management and administration, as well as technical and social service provision on a daily basis. It is one of the largest, most exciting employers in the area and offers great career opportunities. With its 11 faculties and more than 80 departments offering state-of-the-art study programmes grounded in research in a wide range of academic fields, Ghent University is a logical choice for its staff and students.
JOB DESCRIPTION
BioPort is a young and dynamic research group composed of 6 researchers at the Faculty of Bioscience Engineering, Centre for Synthetic Biology of Ghent University focussing on several aspects of Industrial Biotechnology and SynBio. We work on several fundamental and applied topics of microbial transport systems to promote compound membrane crossing, and production of hydrophobic compounds, all in a synthetic biology context (check our website at https://csb-bioport.mystrikingly.com/ and www.csb.ugent.be). You will be hired on the FWO-WEAVE project “Study and engineering of C1 TRansport over Yeast membranes: towards carbon-neutral microbial cell factories (CiTrY)” where you will take the lead in the transporter protein discovery and engineering and coordinate the collaboration with the Austrian project partner.
Below the abstract of the CiTrY project you will be working on:
Microbial cell factories like specialized bacteria, yeast and fungi, are used to produce relevant compounds and engineered biomolecules such as commodities, fine chemicals, food ingredients and biopharmaceuticals. Tailor-made robust microorganisms displaying novel biological behaviors produce these products in a non-chemical way utilizing nature’s toolset, in general using renewable inputs such as glucose or industrial side streams.
C1 feedstocks, such as methane, methanol, formate, CO2 and CO, have important advantages over traditional organic carbon sources like glucose. They are cheap, can be obtained from CO2 in a renewable way, do not compete as food or animal feed and do not require extensive pre-processing from complex agricultural side-streams. Implementing C1 substrates in microbial cell factories would ensure a circular carbon economy that is inherently sustainable. However, due to the relative novelty of this approach, further work will be required to have abiotic C1 substrates compete with biological feedstocks. The CiTrY project will contribute to this goal by investigating and improving transport mechanisms of the C1 substrates over outer and organelle membranes of the microbial cell factories. Underexplored proteins and proteins families will be investigated, advanced protein engineering strategies and high-throughput screening will be conducted, and a novel organelle membrane targeting approach will be developed.
WHAT WE ARE LOOKING FOR
WHAT WE CAN OFFER YOU
INTERESTED?
Apply online through the e-recruitment system before the application deadline (see above). We do not accept late applications or applications that are not submitted through the online system.
Your application must include the following documents:
Note that the maximum file size for each field is 10 MB.
As Ghent University maintains an equal opportunities and diversity policy, everyone is encouraged to apply for this position.
MORE INFORMATION
For more information about this vacancy, please contact Prof. Inge Van Bogaert (Inge.VanBogaert@UGent.be, +32(0)9/264 60 34). Important: do NOT send your application by email, but apply online.
Do you have a question regarding the online application process? Please read our FAQ or contact helpdesk (dpo@ugent.be - tel. 09/264 98 98).
Ghent University is one of the top 100 universities in the Dutch language area, with more than 44,000 students and 15,000 staff members.
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