Academic Positions Italia

CAPICE, Paesi Bassi

12 Early Stage Researcher Positions (for PhD studies) for MSCA-ITN Project “CAPICE”

CAPICE: general description

In this ambitious and inspiring network, 12 Early Stage Researches (ESRs; PhD-level training) will be trained in the broad field of psychiatric genomics, investigating the role of genetics and epigenetics, and their interplay with the environment, in the development and persistence of childhood and adolescent psychopathology. Through biological pathway analyses, drug target validation and the building of prediction models, these results will ultimately be translated to the clinic. Analyses will be performed in large international collaborations, making use of the wealth of data available across a range of European birth and adolescent cohorts.

ESRs will be supervised by leaders in the field located at institutions across Europe in Italy (University of Cagliari), The Netherlands (Vrije Universiteit Amsterdam, Erasmus University Medical Center Rotterdam, University of Twente), Sweden (Karolinska Institute, Gøthenburg University, Janssen Pharmaceutical) and the UK (Imperial College London, King’s College London, University of Bristol). At the end of this project the ESRs will be part of a broad international network consisting of academic and non-academic partners.

Candidates with a background in statistical genetics, bioinformatics, psychology, psychiatry or neuroscience are invited to apply.


Location: Vrije Universiteit Amsterdam, The Netherlands

Vrije Universiteit Amsterdam, department of biological psychology, invites applications for two Early Stage Researcher (ESR) Fellowships for PhD studies funded as part of the Marie Curie European Training Networks, under the European Commission’s H2020 Framework Programme.

  • Project 1: “Polygenic analyses of childhood and adolescent internalizing problems”
    It is known that internalizing symptoms are partly heritable. Polygenic analyses have already shown that these traits are influenced by many genetic variants, each with a small effect. The aim of this project is to identify the common genetic variants and genes that influence the development and course of internalizing symptoms across childhood and adolescence. Another aim is to shed light on the interplay between genetic variants and other risk factors known to be related to internalizing problems, such as birth weight, parental divorce, and parental psychopathology.
  • Project 2: “Polygenic analyses of comorbid symptoms during childhood”
    There is frequent co-morbidity of psychiatric symptoms. This can be concurrent or over time, i.e., internalizing and externalizing symptoms can present simultaneously, but it is also possible that internalizing symptoms are preceded by externalizing symptoms. It has been suggested that this comorbidity is partly explained by genetic variants.

For full job description please click here


Location: King’s College London, United Kingdom

Social, Genetic and Developmental Psychiatry Centre, IOPPN, King’s College London invites applications for an Early Stage Researcher (ESR) Fellowship for a PhD study funded as part of the Marie Curie European Training Networks, under the European Commission’s H2020 Framework Programme.

The recruited ESR will join the CAPICE project: “Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe” (with a 3-year Marie Curie fellowship).

  • Project: “Genetic and environmental underpinnings of psychopathology during childhood and adolescence."
    The student will be based in King’s College London and will be part of the TEDS (The Twins Early Development Study) research team (https://www.teds.ac.uk/research), supervised by Professor Robert Plomin. The student will be expected to develop high-level skills in quantitative and molecular genetic analysis. The specific aim of this project is to unravel the developmental underpinnings of childhood and adolescent psychopathology and the co-morbidity of these problems by conducting multivariate and longitudinal twin analyses. The role of gene-environment interaction in the development of childhood psychopathology will be investigated using molecular genetic methodology. Data from TEDS will be combined with data from other European birth cohorts collaborating in CAPICE.

For full job description please click here


Location: University of Gothenburg, Sweden

Gøthenburg University invites applications for one Early Stage Researcher (ESR) Fellowship for a PhD study funded as part of the Marie Curie European Training Networks, under the European Commission’s H2020 Framework Programme.

  • Project: “Prediction of negative life outcomes in individuals with anxiety”
    The overarching goal of this project is to develop prediction models to identify individuals with anxiety/anxiety-symptomatology that are in need of special attention with regards to high likelihood of developing negative life outcomes. In addition, the project aims to understand and depict the features that characterize the group of individuals with anxiety/anxiety-symptomatology with a high likelihood of developing negative life outcomes.

    The specific aims are to (via prediction models and descriptive statistics using detailed assessments):
    1. Predict common negative outcomes (e.g. mental health problems and poor school achievement) in adolescence in individuals with anxiety.
    2. Predict rare negative outcomes (e.g. suicide attempts and criminality) in adolescence and early adulthood in individuals with anxiety.

    The ESR will learn to work with, and combine, several types of data; surveys, national registers, and genomic. The ESR will apply standard epidemiological statistical methods (linear-, logistic-, and Coxregression).

For full job description please click here


Location: University of Bristol, United Kingdom

University of Bristol invites applications for two Early Stage Researcher (ESR) Fellowships for PhD studies funded as part of the Marie Curie European Training Networks, under the European Commission’s H2020 Framework Programme.

The recruited ESRs will join the CAPICE project: “Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe” (with a 3-year Marie Curie fellowship).

  • Project 1 Lifestyle behaviours during pregnancy and offspring psychiatric outcomes: Using Mendelian randomization to infer causality.
    The aim of this project is to explore the relationships between lifestyle behaviours in the mother during pregnancy (e.g., tobacco and alcohol use) and later psychiatric outcomes in the offspring through childhood and into early adulthood.
  • Project 2 Two-step Mendelian randomization analyses of lifestyle behaviours during pregnancy and offspring psychiatric outcomes.
    The aim of this project is to conduct two-step Mendelian randomization analyses of lifestyle behaviours in the mother during pregnancy, to determine whether DNA methylation mediates the relationship between exposures in pregnancy and psychiatric outcomes in the offspring.

For full job description please click here


Location: Erasmus University, Rotterdam, The Netherlands

The Department of Child and Adolescent Psychiatry at Erasmus MC, Rotterdam, invites applications for an Early Stage Researcher (ESR) Fellowship for a PhD study funded as part of the Marie Curie European Training Networks, under the European Commission’s H2020 Framework Programme.

  • Project “A genetic and epigenetic approach to studying the effects of lifestyle behaviors during pregnancy on offspring outcomes”
    The specific aims of this project are to study the effects of lifestyle behaviors during pregnancy on offspring outcomes. Outcomes of interest include DNA methylation signatures as well as psychiatric outcomes in childhood and adolescence. In particular, the candidate will work with experts in Mendelian randomization methods and psychiatric epidemiology; information on the mentors can be found on their faculty websites.

For full job description please click here


Location: Karolinska Institutet, Stockholm, Sweden

Karolinska Institutet invites applications for one Early Stage Researcher (ESR) Fellowship for a PhD study funded as part of the Marie Curie European Training Networks, under the European Commission’s H2020 Framework Programme.

  • Project “Prediction of negative life outcomes in ADHD”
    The overarching goal of this project is to develop prediction models to identify the individuals with ADHD/ADHD-symptomatology in need for special attention as well as understand the features that characterize the group of individuals with ADHD with high likelihood of developing negative outcomes.
    The specific aims are to apply machine learning techniques using detailed assessments of predictors and outcomes to:
    1. Predict common negative outcomes (e.g. mental health problems and poor school achievement) in adolescence in individuals with ADHD.
    2. Predict rare and severe negative outcomes (e.g. suicide attempts and criminality) in adolescence and early adulthood in individuals with ADHD.

For full job description please click here


Location: University of Twente, Enschede, The Netherlands

The University of Twente invites applications for an Early Stage Researcher (ESR) Fellowship for a PhD study funded as part of the Marie Curie European Training Networks, under the European Commission’s H2020 Framework Programme.

  • Project “Gene-environment interaction using harmonized phenotypes”
    The CAPICE projects uses data that were gathered using different questionnaires to assess psychopathology. To optimally combine all available assessments, one of specific aims of this project is to harmonize these phenotypic data within cohorts and within age groups. The next aim is to elucidate the complex interplay of genetic liability and environmental factors in causing childhood psychopathology, using these harmonized scores.

For full job description please click here


Location: University of Cagliari, Sardinia, Italy

UNIVERSITY OF CAGLIARI invites applications for one Early Stage Researcher (ESR) Fellowship for a PhD study funded as part of the Marie Curie European Training Networks, under the European Commission’s H2020 Framework Programme.

  • Project “Building a sustainable facility for multi-site analyses and translating the results to the clinic ”
    There has been a clear shift from researchers conducting studies in their own labs to large-scale collaborative studies in consortia. This will remain the rule in (epi)geneticas well as in other kind of analyses. To perform these multi-site analyses most efficiently, the aim is to build a facility that allows analyzing all data available over sites without necessarily having access to the raw data.

For full job description please click here


Location: Imperial College London, United Kingdom

Imperial College London invites applications for an Early Stage Researcher (ESR) Fellowship for a PhD study funded as part of the Marie Curie European Training Networks, under the European Commission’s H2020 Framework Programme.

  • Project: Analytical methods for bio-behavioural sciences - polygenic analyses of childhood and adolescent ADHD symptoms
    It is known that ADHD and related traits are highly heritable. Polygenic analyses have already shown that these traits are influenced by many genetic variants, each with a small effect size. The aim of this project is to identify the common genetic variants and genes that influence the development and course of ADHD symptoms across childhood and adolescence.

For full job description please click here


Location: Janssen Pharmaceuticals, Stockholm, Sweden
(in cooperation with Karolinska Institutet)

Janssen Pharmaceuticals and Karolinska Institutet invite applications for one Early Stage Researcher (ESR) Fellowship for a PhD study funded as part of the Marie Curie European Training Networks, under the European Commission’s H2020 Framework Programme.

  • Project “Biological pathways for drug target validation in mood disorders”
    The Neuroscience Therapeutic Area at Janssen Research & Development is committed to the discovery and development of novel therapeutics for mood disorders. Because these mood disorders are heritable, a promising approach for identifying potential molecular targets for new treatments involves elucidation of the genetic risk and resilience factors that influence the pathogenesis of these conditions. The ultimate aim of the project is clinical translation, through biological pathway analyses, drug target validation and predictive modeling. The CAPICE consortium data provide a unique opportunity for these analyses and modeling.

For full job description please click here


CAPICE

In this ambitious and inspiring network, 12 Early Stage Researches (ESRs; PhD-level training) will be trained in the broad field of psychiatric genomics, investigating the role of genetics and epigenetics.

Dettagli

Data pubblicazione:
2017-02-09
Scadenza:
2017-03-01

Please see job description

Ti preghiamo di indicare Academic Positions nella tua candidatura.

Offerte simili